Working at the interface between biology and computer science, the Dessimoz Lab seeks to better understand evolutionary and functional relationships between genes, genomes, and species. The Waterhouse Group is focused on elucidating interactions between gene evolution and gene function through computational interrogation of arthropod genomics data. Both Groups are members of the SIB – Swiss Institute of Bioinformatics.
The two Postdocs will lead the evolutionary genomics contributions to a groundbreaking interdisciplinary project in collaboration with the Group of Prof. Bruno Lemaitre at the neighbouring École Polytechnique Fédérale de Lausanne.
The overall project aims to develop the computational tools required to fully exploit new genomics data in a framework that also takes advantage of the latest molecular biology tools to achieve combined evolutionary and functional characterisation of the Drosophila immune system. The two Postdocs will work closely together on the project developing and applying comparative genomics and evolutionary modelling approaches to fully exploit new genomics data, with a biological focus on the insect innate immune system. The evolutionary genomics part of the project will focus on (1) extending our current knowledge of immune effectors beyond the canonical repertoires of genes encoding for known antimicrobial peptides, and (2) exploiting the rich genomics datasets across Drosophila species to trace the evolutionary histories of immune genes.
We seek candidates with demonstrated programming skills in the areas of bioinformatics, computational biology, and comparative genomics. Further desirable attributes include knowledge of and interest in orthology delineation, gene family evolution, phylogenetics, gene birth/death, genome-wide synteny, selection and constraint, gene prediction, genome annotation, immunity, infection, insects.
Applications can only be made through the University of Lausanne online recruitment platform, where the full job descriptions will be posted shortly.